Category: Metabolic
Body recomp via NNMT inhibition
Mechanism: Inhibits NNMT, shifts methyl/NAD metabolism
Typical dose: 250-500 mcg daily
Cycle length: 4-6 weeks
Frequency: Daily
Benefits: Fat loss, Metabolic flexibility, Insulin sensitivity
Synergistic compounds: NAD+, AOD-9604, L-Carnitine, MOTS-c, Retatrutide, Tesamorelin
Category: Cognitive & Nootropic
High-potency Semax analog
Mechanism: Adamantyl-modified neurotrophic peptide; BDNF/TrkB and dopamine optimization
Typical dose: 50-150 mcg daily
Cycle length: 2 weeks
Frequency: Daily
Benefits: Cognitive drive, Extended focus (10-20h), Neuroplasticity
Synergistic compounds: Selank
Category: Metabolic
Fat mobilization support
Mechanism: Lipolysis signaling via GH C-terminal fragment
Typical dose: 250-500 mcg daily
Cycle length: 12-16 weeks
Frequency: Daily
Benefits: Fat mobilization, Gentle cut support, No hyperglycemia
Synergistic compounds: 5-Amino-1MQ, L-Carnitine, NAD+, Retatrutide, Tesamorelin, Tirzepatide
Category: Healing & Tissue Repair
Neuropathic pain & nerve healing
Mechanism: Innate repair receptor agonist, tissue-protective signaling
Typical dose: 4 mg daily
Cycle length: 4-12 weeks
Frequency: Daily
Benefits: Neuropathic pain reduction, Nerve injury recovery, Improved sleep
Synergistic compounds: NAD+, SS-31, BPC-157
Category: Healing & Tissue Repair
Body protection compound
Mechanism: Angiogenesis, NO signaling, fibroblast migration
Typical dose: 250-500 mcg daily
Cycle length: 4-12 weeks
Frequency: Daily
Benefits: Systemic healing, Gut barrier support, Tissue regeneration
Synergistic compounds: TB-500, GHK-Cu, NAD+, KPV, ARA-290, Cartalax, PEA, Thymosin Beta-4
Category: Healing & Tissue Repair
Cartilage & joint support
Mechanism: Gene-expression normalization in chondrocytes
Typical dose: 2 mg daily
Cycle length: 4-8 weeks
Frequency: Daily
Benefits: Joint comfort, Cartilage symptoms, Reduced stiffness
Synergistic compounds: NAD+, BPC-157, GHK-Cu, TB-500
Category: Growth Hormone Axis
Extended GHRH analog for pulsatile GH
Mechanism: GHRH-R agonist with albumin-binding DAC tail; 5-8 day half-life
Typical dose: 2-4 mg weekly
Cycle length: 4-12 weeks
Frequency: Weekly
Benefits: Pulsatile GH restoration, Body recomposition, Deep sleep improvement
Synergistic compounds: Ipamorelin
Category: Growth Hormone Axis
Short-acting GHRH analog (Mod GRF 1-29)
Mechanism: GHRH-R agonist; ~30 min half-life, daily/multi-daily cadence
Typical dose: 100-300 mcg daily
Cycle length: 8-12 weeks
Frequency: Daily
Benefits: Pulsatile GH release, Sleep & recovery, Daily-cadence GHRH
Synergistic compounds: Ipamorelin
Category: Cognitive & Nootropic
Sleep onset & circadian support
Mechanism: Modulates sleep-arousal networks via hypothalamic signaling
Typical dose: 100-400 mcg daily
Cycle length: 2-4 weeks
Frequency: Daily
Benefits: Faster sleep onset, Fewer awakenings, Improved sleep continuity
Synergistic compounds: Oxytocin, Pinealon, Selank, Semax, VIP
Category: Anti-Aging
Circadian & longevity support
Mechanism: Telomere/clock-gene regulation, melatonin modulation
Typical dose: 5-10 mg daily
Cycle length: 1.5-3 weeks
Frequency: Daily
Benefits: Sleep quality, Circadian regularity, Stress resilience
Synergistic compounds: Pinealon, Thymalin
Category: Anti-Aging
Senolytic research peptide (preclinical)
Mechanism: D-retro-inverso TAT-fused peptide; disrupts FOXO4-p53 to clear senescent cells
Typical dose: 1-5 mg every 3 days
Cycle length: 1-2 weeks
Frequency: Every 3 days
Benefits: Senescent cell clearance (mouse), Tissue function rebound (mouse), Inflammation modulation (mouse)
Synergistic compounds: NAD+, SS-31, MOTS-c, Epitalon, Pinealon, GHK-Cu, Thymosin α-1
Category: Cosmetic
Collagen synthesis & skin remodeling
Mechanism: Up-regulates collagen/elastin, down-modulates MMPs
Typical dose: 1-2.5 mg 3×/week
Cycle length: 6-8 weeks
Frequency: 3×/week
Benefits: Skin remodeling, Scar quality, Hair support
Synergistic compounds: BPC-157, TB-500, NAD+, Cartalax, KPV, Thymosin Beta-4
Category: Growth Hormone Axis
Legacy ghrelin-receptor GH pulse
Mechanism: GHS-R1a agonist; GH pulse with cortisol/prolactin spillover
Typical dose: 100-300 mcg daily
Cycle length: 8-12 weeks
Frequency: Daily
Benefits: GH pulse amplification, Appetite stimulation, Legacy class comparator
Synergistic compounds: Sermorelin
Category: Growth Hormone Axis
Older appetite-heavy GH secretagogue
Mechanism: GHS-R1a agonist; heavier hunger, cortisol, and prolactin than newer agents
Typical dose: 100-300 mcg daily
Cycle length: 8-12 weeks
Frequency: Daily
Benefits: Hunger and weight gain, GH pulse, Class comparator
Synergistic compounds: Sermorelin
Category: Immune Modulators
Master antioxidant & detox substrate
Mechanism: Tripeptide redox buffer; NADPH-dependent recycling; phase 2 detox conjugation
Typical dose: 200-600 mg 3×/week
Cycle length: 4-12 weeks
Frequency: 3×/week
Benefits: Oxidative stress protection, Detoxification support, Mitochondrial function
Synergistic compounds: NAD+, KPV, PEA, Thymosin α-1, Thymulin, VIP
Category: HPTA Axis
Testicular maintenance & fertility
Mechanism: Mimics LH; stimulates Leydig/theca cells
Typical dose: 150-500 IU every other day
Cycle length: 3-24 weeks
Frequency: Every other day
Benefits: Testicular volume maintenance, Libido, Semen quality
Synergistic compounds: Kisspeptin-10
Category: Growth Hormone Axis
Master anabolic hormone
Mechanism: 191-aa pituitary hormone; JAK2/STAT5; IGF-1 axis
Typical dose: 0.5-4 IU daily
Cycle length: 8-12 weeks
Frequency: Daily
Benefits: Body recomposition, Cellular regeneration, Deep sleep & skin/bone health
Synergistic compounds: NAD+, BPC-157, TB-500, GHK-Cu, L-Carnitine, MOTS-c, SS-31
Category: Growth Hormone Axis
Myogenic driver for tissue repair
Mechanism: Modified IGF-1 with extended half-life; PI3K-Akt-mTOR; satellite-cell proliferation
Typical dose: 20-80 mcg daily
Cycle length: 3-4 weeks
Frequency: Daily
Benefits: Muscle repair, Satellite cell activation, Collagen synthesis
Synergistic compounds: BPC-157, TB-500, Tesamorelin, Ipamorelin
Category: Growth Hormone Axis
Clean GH secretagogue
Mechanism: Selective GHS-R agonist; GH release without prolactin/cortisol
Typical dose: 100-300 mcg daily
Cycle length: 8-12 weeks
Frequency: Daily
Benefits: Deeper sleep, Enhanced recovery, Improved training capacity
Synergistic compounds: GLP-1s, CJC-1295 no-DAC, Sermorelin, Tesamorelin, CJC-1295 DAC
Category: HPTA Axis
HPG-axis support
Mechanism: Stimulates GnRH neurons; pulsatile LH/FSH release
Typical dose: 100-500 mcg 3×/week
Cycle length: 4-8 weeks
Frequency: 3×/week
Benefits: Libido improvement, LH/FSH elevation, Testicular function
Synergistic compounds: hCG
Category: Healing & Tissue Repair
Anti-inflammatory peptide
Mechanism: α-MSH fragment, NF-κB down-regulation, mast-cell stabilization
Typical dose: 200-500 mcg daily
Cycle length: 4-8 weeks
Frequency: Daily
Benefits: Mucosal inflammation, IBD symptom support, Post-injury swelling
Synergistic compounds: VIP, BPC-157, GHK-Cu, Glutathione (GSH), PEA, Selank, TB-500, Thymosin Beta-4
Category: Metabolic
Fat oxidation & endurance
Mechanism: Carnitine shuttle for fatty-acid transport into mitochondria
Typical dose: 200-500 mg daily
Cycle length: 4-12 weeks
Frequency: Daily
Benefits: Fat oxidation, Endurance enhancement, Muscle recovery
Synergistic compounds: GLP-1s, MOTS-c, NAD+, 5-Amino-1MQ, AOD-9604, SS-31, Tesamorelin
Category: Cosmetic
MC1R-selective photoprotector
Mechanism: Selective MC1R agonist; eumelanin synthesis; DNA repair enhancement
Typical dose: 500-1000 mcg 2×/week
Cycle length: 2-8 weeks
Frequency: 2×/week
Benefits: UV-independent tanning, Photoprotection, DNA repair support
Synergistic compounds: GHK-Cu, KPV, NAD+
Category: Cosmetic
Non-selective melanocortin agonist (unapproved)
Mechanism: Cyclic peptide; activates MC1R/MC3R/MC4R/MC5R — tanning, sexual function, appetite suppression
Typical dose: 250-500 mcg daily
Cycle length: 1-4 weeks
Frequency: Daily
Benefits: Tanning without UV, Sexual function, Appetite reduction
Synergistic compounds:
Category: Growth Hormone Axis
Oral ghrelin-receptor GH secretagogue
Mechanism: Small-molecule GHS-R1a agonist; raises GH and IGF-1 orally
Typical dose: 10-25 mg daily
Cycle length: 8-104 weeks
Frequency: Daily
Benefits: Lean mass gain, GH/IGF-1 elevation, Oral convenience
Synergistic compounds: BPC-157, NAD+
Category: Metabolic
Mitochondrial peptide for metabolic flexibility
Mechanism: AMPK activation, metabolic flexibility enhancement
Typical dose: 5-10 mg 2-3x-weekly
Cycle length: 8-12 weeks
Frequency: 2-3x-weekly
Benefits: Fat oxidation, Training tolerance, Metabolic flexibility
Synergistic compounds: GLP-1s, NAD+, SS-31, L-Carnitine, 5-Amino-1MQ, Tesamorelin
Category: Anti-Aging
Foundational energy substrate
Mechanism: Universal cofactor for ATP and sirtuin activity
Typical dose: 50-250 mg 2-3x-weekly
Cycle length: 2-12 weeks
Frequency: 2-3x-weekly
Benefits: Restores cellular energy, Supports DNA repair, Enhances mitochondrial function
Synergistic compounds: GLP-1s, MOTS-c, SS-31, L-Carnitine, BPC-157, 5-Amino-1MQ, Glutathione (GSH), Thymosin α-1
Category: HPTA Axis
Bonding & autonomic state signal
Mechanism: OXTR agonism; threat processing, social salience, autonomic state
Typical dose: 10-20 IU as needed
Cycle length: On-demand
Frequency: As needed
Benefits: Anxiety/social context support, HPA recovery, Libido (off-label)
Synergistic compounds: DSIP, Pinealon, Selank, PT-141, VIP
Category: Cognitive & Nootropic
Neuroplasticity enhancer
Mechanism: BDNF upregulation, synaptic plasticity enhancement
Typical dose: 100-500 mcg daily
Cycle length: 4-8 weeks
Frequency: Daily
Benefits: Motor learning, Neuroplasticity, Post-TBI recovery
Synergistic compounds: Semax, NAD+, SS-31
Category: Healing & Tissue Repair
Anti-inflammatory fatty-acid amide (oral)
Mechanism: PPAR-α activation, mast-cell ALIA signaling, TRPV1 modulation
Typical dose: 300-600 mg bid
Cycle length: 8-12 weeks
Frequency: BID
Benefits: Chronic pain reduction, Neuropathic pain support, Gut-barrier modulation
Synergistic compounds: BPC-157, Glutathione (GSH), KPV, Selank, VIP
Category: Anti-Aging
CNS trophic support
Mechanism: Oligopeptide regulatory effects on brain tissue
Typical dose: 1-2 mg daily
Cycle length: 2-3 weeks
Frequency: Daily
Benefits: Cognitive support, Neuroprotection, Stress resilience
Synergistic compounds: DSIP, Epitalon, Oxytocin, Selank, Semax, VIP
Category: HPTA Axis
Sexual desire signal (FDA-approved HSDD)
Mechanism: Non-selective melanocortin agonist; central arousal circuitry
Typical dose: 1.75 mg as needed
Cycle length: On-demand
Frequency: As needed
Benefits: Desire & arousal (women), Erectile support (off-label), On-demand dosing
Synergistic compounds: Oxytocin
Category: GLP-1 Agonists
Triple agonist for aggressive fat loss
Mechanism: GLP-1 (satiety), GIP (insulinotropic), glucagon (lipolysis) agonist
Typical dose: 0.25-12 mg weekly
Cycle length: 12-48 weeks
Frequency: Weekly
Benefits: Aggressive fat loss, Energy expenditure, Satiety control
Synergistic compounds: NAD+, Tesamorelin, MOTS-c, L-Carnitine, 5-Amino-1MQ, AOD-9604, Ipamorelin, SS-31
Category: Cognitive & Nootropic
Anxiolytic & stress resilience
Mechanism: Tuftsin analog, GABAergic modulation, anti-inflammatory
Typical dose: 250-500 mcg daily
Cycle length: 2-4 weeks
Frequency: Daily
Benefits: Anxiety reduction, Stress resilience, Improved mood
Synergistic compounds: Semax, Adamax, DSIP, KPV, Oxytocin, Pinealon, Thymosin α-1, VIP
Category: GLP-1 Agonists
GLP-1 for weight loss & CV protection
Mechanism: GLP-1R agonism with long half-life
Typical dose: 0.1-2.4 mg weekly
Cycle length: 12-68 weeks
Frequency: Weekly
Benefits: Weight loss, Glycemic control, CV risk reduction
Synergistic compounds: NAD+, MOTS-c, L-Carnitine, Tesamorelin, AOD-9604, Ipamorelin
Category: Cognitive & Nootropic
Cognitive drive & focus
Mechanism: ACTH analog, BDNF up-regulation, dopaminergic modulation
Typical dose: 200-600 mcg daily
Cycle length: 2 weeks
Frequency: Daily
Benefits: Cognitive drive, Focus enhancement, Post-TBI support
Synergistic compounds: Selank, P21, DSIP, NAD+, Pinealon, SS-31
Category: Growth Hormone Axis
Pulsatile GH release
Mechanism: Pulsatile GH release from pituitary, modest IGF-1 rise
Typical dose: 200-500 mcg daily
Cycle length: 8-12 weeks
Frequency: Daily
Benefits: Sleep quality, Enhanced recovery, Modest body composition
Synergistic compounds: Ipamorelin, GHRP-2, GHRP-6, NAD+
Category: Anti-Aging
Mitochondrial function optimizer
Mechanism: Binds cardiolipin, stabilizes cristae, improves electron transport
Typical dose: 5-10 mg daily
Cycle length: 8-12 weeks
Frequency: Daily
Benefits: Reduces fatigue, Improves HRV, Lowers post-exertional malaise
Synergistic compounds: MOTS-c, NAD+, L-Carnitine, P21, Semax, TB-500
Category: Healing & Tissue Repair
Soft-tissue healing accelerator
Mechanism: Actin-sequestering, cell migration, angiogenesis
Typical dose: 2-4 mg 2×/week
Cycle length: 4-8 weeks
Frequency: 2×/week
Benefits: Soft-tissue healing, Post-surgical recovery, Anti-inflammatory
Synergistic compounds: BPC-157, GHK-Cu, NAD+, Cartalax, KPV, SS-31
Category: Growth Hormone Axis
Visceral fat reduction via GH
Mechanism: Stimulates pituitary GH release, IGF-1 elevation, lipolysis
Typical dose: 1-2 mg daily
Cycle length: 12-16 weeks
Frequency: Daily
Benefits: Visceral fat reduction, Improved body composition, Enhanced recovery
Synergistic compounds: GLP-1s, Ipamorelin, NAD+, 5-Amino-1MQ, AOD-9604, BPC-157, L-Carnitine, MOTS-c
Category: Immune Modulators
Russian thymic extract complex
Mechanism: Short thymic peptides (KE, EW, EDP fractions); transcription and hematopoietic signaling
Typical dose: 5-20 mg daily
Cycle length: 4-11 days
Frequency: Daily
Benefits: Immune restoration, Autoimmune baseline support, Acute illness recovery
Synergistic compounds: Epitalon
Category: Healing & Tissue Repair
Full-length TB-4 (verify vs TB-500 fragment)
Mechanism: G-actin sequestration, Ac-SDKP release, anti-fibrotic signaling
Typical dose: 2-4 mg 2×/week
Cycle length: 4-8 weeks
Frequency: 2×/week
Benefits: Soft-tissue repair, Anti-fibrotic action, Wound and ophthalmic trial use
Synergistic compounds: BPC-157, GHK-Cu, KPV
Category: Immune Modulators
Immune modulation & post-viral support
Mechanism: Enhances T-cell function, upregulates MHC, rebalances Th1/Th2
Typical dose: 1.6 mg daily
Cycle length: 12-24 weeks
Frequency: Daily
Benefits: Infection frequency reduction, Faster viral recovery, Improved energy
Synergistic compounds: NAD+, Glutathione (GSH), Selank, Thymulin
Category: Immune Modulators
Zinc-dependent thymic immune signal
Mechanism: T-cell differentiation, NK cell activity, neuroendocrine stress-immune crosstalk
Typical dose: 5-10 mg daily
Cycle length: 1-2 weeks
Frequency: Daily
Benefits: T-cell maturation, Immune-stress balance, NK cell support
Synergistic compounds: Glutathione (GSH), NAD+, Thymosin α-1
Category: GLP-1 Agonists
Dual agonist for weight & T2D control
Mechanism: GLP-1 satiety/gastric delay + GIP insulinotropic effects
Typical dose: 0.5-15 mg weekly
Cycle length: 12-72 weeks
Frequency: Weekly
Benefits: Weight loss, Glycemic control, OSA improvement
Synergistic compounds: NAD+, MOTS-c, L-Carnitine, Tesamorelin, AOD-9604, Ipamorelin
Category: Immune Modulators
MCAS & dysautonomia support
Mechanism: VPAC receptor activation; anti-inflammatory; mast-cell modulation
Typical dose: 25-200 mcg daily
Cycle length: 4-12 weeks
Frequency: Daily
Benefits: Heat intolerance reduction, Brain fog reduction, HRV improvement
Synergistic compounds: KPV, DSIP, Glutathione (GSH), NAD+, Oxytocin, PEA, Pinealon, Selank