.dosing-page-wrapper{min-height:100vh;background:var(--color-page-tool)}.dosing-section{display:flex;flex-direction:column;gap:var(--space-xl)}.dosing-section-title{font-size:var(--text-headline-md);font-weight:600;color:var(--color-text-primary);letter-spacing:-.02em}@media (min-width:768px){.dosing-section-title{font-size:1.25rem}}.dosing-drug-grid{display:grid;grid-template-columns:1fr;gap:var(--space-md)}@media (min-width:768px){.dosing-drug-grid{grid-template-columns:repeat(3,1fr)}}.dosing-drug-card{border:1px solid var(--color-border-soft);border-radius:var(--radius-card);background:var(--color-surface);padding:1.5rem;cursor:pointer;transition:all var(--motion-fast)}@media (min-width:768px){.dosing-drug-card{padding:2rem}}.dosing-drug-card:hover{background:var(--color-accent-light);border-color:var(--color-accent-primary);transform:translateY(-4px)}.dosing-drug-card:focus-visible{outline:4px solid var(--color-accent-primary);outline-offset:4px}.dosing-drug-card-active{border-color:var(--color-accent-primary);background:var(--color-accent-medium)}.dosing-drug-card-disabled{opacity:.6;cursor:not-allowed}.dosing-drug-card-disabled,.dosing-drug-card-disabled:hover{background:var(--color-surface);border-color:var(--color-border)}.dosing-drug-card-disabled:hover{transform:none}.dosing-drug-badge{display:inline-block;padding:var(--space-xxs) var(--space-sm);border-radius:var(--radius-sm);font-size:var(--text-badge);font-weight:600;text-transform:uppercase;letter-spacing:.05em}.dosing-frequency-grid{display:grid;grid-template-columns:1fr;gap:var(--space-md)}@media (min-width:768px){.dosing-frequency-grid{grid-template-columns:repeat(2,1fr)}}@media (min-width:1024px){.dosing-frequency-grid{grid-template-columns:repeat(4,1fr)}}.dosing-frequency-card{border:1px solid var(--color-border-soft);border-radius:var(--radius-card);background:var(--color-surface);padding:1.5rem;cursor:pointer;transition:all var(--motion-fast)}@media (min-width:768px){.dosing-frequency-card{padding:2rem}}.dosing-frequency-card:hover{border-color:var(--color-info);background:var(--color-info-tint)}.dosing-frequency-card:focus-visible{outline:4px solid var(--color-info);outline-offset:4px}.dosing-frequency-card-active{border-color:var(--color-info);background:var(--color-info-tint)}.dosing-frequency-label{font-size:var(--text-body-md);font-weight:600;color:var(--color-text-primary)}.dosing-frequency-description{font-size:var(--text-body-sm);color:var(--color-text-secondary);line-height:var(--leading-normal)}.dosing-dose-selector{display:flex;flex-direction:column;gap:var(--space-md)}.dosing-dose-option{min-height:44px;padding:var(--space-btn-y) var(--space-btn-x);border:1px solid var(--color-border-soft);border-radius:var(--radius-md);background:var(--color-surface);font-size:var(--text-body-md);font-weight:500;color:var(--color-text-primary);cursor:pointer;transition:all var(--motion-fast);text-align:center}.dosing-dose-option:hover{border-color:var(--color-accent-primary);background:var(--color-accent-light);transform:scale(.98)}.dosing-dose-option:focus-visible{outline:4px solid var(--color-accent-primary);outline-offset:4px}.dosing-dose-option-active{border-color:var(--color-accent-primary);background:var(--color-accent-primary);color:var(--color-text-inverse)}.dosing-dose-option:disabled{opacity:.6;cursor:not-allowed;border-color:var(--color-border);background:var(--color-surface)}.dosing-dose-category-label{font-size:var(--text-label-sm);font-weight:700;text-transform:uppercase;letter-spacing:.08em;color:var(--color-text-secondary)}.dosing-metrics-grid{display:grid;grid-template-columns:1fr;gap:var(--space-md)}@media (min-width:768px){.dosing-metrics-grid{grid-template-columns:repeat(2,1fr)}}@media (min-width:1024px){.dosing-metrics-grid{grid-template-columns:repeat(2,1fr)}}.dosing-metric-card{border:1px solid var(--color-border-soft);border-radius:var(--radius-card);background:var(--color-surface);padding:var(--space-lg)}@media (min-width:768px){.dosing-metric-card{padding:var(--space-xl)}}.dosing-metric-label{font-size:var(--text-label-sm);font-weight:700;text-transform:uppercase;letter-spacing:.08em;color:var(--color-text-secondary);margin-bottom:8px}.dosing-metric-value{font-size:1.5rem;font-weight:500;color:var(--color-text-primary);line-height:1.125;font-variant-numeric:tabular-nums;font-feature-settings:"tnum" 1}@media (min-width:768px){.dosing-metric-value{font-size:var(--text-result-lg)}}.dosing-metric-unit{font-size:var(--text-caption);color:var(--color-text-secondary);font-weight:400}.dosing-chart-container{height:384px;background:var(--color-surface);border:1px solid var(--color-border-soft);border-radius:var(--radius-card);padding:var(--space-lg);overflow:hidden}.dosing-chart-title{font-size:var(--text-headline-sm);font-weight:600;color:var(--color-text-primary);margin-bottom:var(--space-md)}.dosing-legend{display:flex;flex-direction:row;gap:var(--space-lg);flex-wrap:wrap}.dosing-legend-item{display:flex;align-items:center;gap:var(--space-xs);font-size:var(--text-body-sm);color:var(--color-text-secondary)}.dosing-adjustment-section{display:flex;flex-direction:column;gap:var(--space-md)}.dosing-adjustment-button{min-height:44px;padding:var(--space-btn-y) var(--space-btn-x);border:4px solid var(--color-border);border-radius:var(--radius-md);background:var(--color-surface);cursor:pointer;transition:all var(--motion-fast);font-size:var(--text-body-md);font-weight:500;color:var(--color-text-primary)}.dosing-adjustment-button:hover{border-color:var(--color-info);background:var(--color-info-tint)}.dosing-adjustment-button:disabled{opacity:.4;cursor:not-allowed}.dosing-adjustment-active{border-color:var(--color-info);background:var(--color-info-tint)}.dosing-adjustment-mobile{display:grid;grid-template-columns:1fr;gap:var(--space-sm)}@media (min-width:768px){.dosing-adjustment-mobile{display:none}}.dosing-adjustment-desktop{display:none}@media (min-width:768px){.dosing-adjustment-desktop{display:grid;grid-template-columns:repeat(4,1fr);gap:var(--space-md);align-items:center}}.dosing-adjustment-remove{min-width:44px;min-height:44px;border:1px solid var(--color-error);border-radius:50%;background:var(--color-surface);color:var(--color-error);cursor:pointer;transition:all var(--motion-fast);display:flex;align-items:center;justify-content:center}.dosing-adjustment-remove:hover{background:var(--color-error-tint)}.dosing-adjustment-input{min-height:44px;padding:var(--space-input);border:1px solid var(--color-border-soft);border-radius:var(--radius-md);background:var(--color-surface);font-size:var(--text-body-md);color:var(--color-text-primary);text-align:center}.dosing-adjustment-input:focus{outline:4px solid var(--color-accent-primary);outline-offset:4px;border-color:var(--color-accent-primary)}.dosing-adjustment-label{font-size:var(--text-label-md)}.dosing-adjustment-label,.dosing-drawer-button{font-weight:500;color:var(--color-text-primary)}.dosing-drawer-button{min-height:44px;padding:var(--space-btn-y) var(--space-btn-x);border:1px solid var(--color-border-soft);border-radius:var(--radius-md);background:var(--color-surface);cursor:pointer;transition:all var(--motion-fast);font-size:var(--text-body-md);width:100%;text-align:left;display:flex;align-items:center;justify-content:space-between}.dosing-drawer-button:hover{border-color:var(--color-border-bold);background:var(--color-surface-subtle)}.dosing-drawer-panel{padding:var(--space-lg);border:1px solid var(--color-border-soft);border-top:none;border-radius:0 0 var(--radius-md) var(--radius-md);background:var(--color-surface)}.dosing-table{width:100%;border-collapse:collapse;font-size:var(--text-body-sm)}.dosing-table-cell{padding:var(--space-sm) var(--space-md);border:1px solid var(--color-border-soft);text-align:left;vertical-align:top}.dosing-banner-info{border-left:4px solid var(--color-info);background:var(--color-info-tint)}.dosing-banner-info,.dosing-banner-warning{padding:var(--space-md);border-radius:var(--radius-sm)}.dosing-banner-warning{border-left:4px solid var(--color-warning);background:var(--color-warning-tint)}.dosing-banner-alert{border-left:4px solid var(--color-error);background:var(--color-error-tint);padding:var(--space-md);border-radius:var(--radius-sm)}.dosing-benefit-card{border:1px solid var(--color-info);border-radius:var(--radius-card)}.dosing-benefit-card,.dosing-tradeoff-card{background:var(--color-surface);padding:var(--space-lg)}.dosing-tradeoff-card{border:1px solid var(--color-error);border-radius:var(--radius-card)}.dosing-consideration-card{border:1px solid var(--color-accent-primary);background:var(--color-surface);padding:var(--space-lg);border-radius:var(--radius-card)}.dosing-pill-blue{background:var(--color-glp1)}.dosing-pill-blue,.dosing-pill-purple{display:inline-block;padding:var(--space-xxs) var(--space-sm);border-radius:var(--radius-pill);color:var(--color-text-inverse);font-size:var(--text-badge);font-weight:600;text-transform:uppercase;letter-spacing:.05em}.dosing-pill-purple{background:var(--pf-blue)}.dosing-pill-red{display:inline-block;padding:var(--space-xxs) var(--space-sm);border-radius:var(--radius-pill);background:var(--color-error);color:var(--color-text-inverse);font-size:var(--text-badge);font-weight:600;text-transform:uppercase;letter-spacing:.05em}.dosing-stability-badge-low{background:var(--color-success)}.dosing-stability-badge-low,.dosing-stability-badge-medium{display:inline-block;padding:var(--space-xxs) var(--space-sm);border-radius:var(--radius-sm);color:var(--color-text-inverse);font-size:var(--text-badge);font-weight:600}.dosing-stability-badge-medium{background:var(--color-warning)}.dosing-stability-badge-high{display:inline-block;padding:var(--space-xxs) var(--space-sm);border-radius:var(--radius-sm);background:var(--color-error);color:var(--color-text-inverse);font-size:var(--text-badge);font-weight:600}.dosing-icon-sm{width:12px;height:12px}.dosing-icon-md{width:16px;height:16px}.dosing-icon-lg{width:20px;height:20px}.dosing-icon-xs{width:12px;height:12px}.dosing-flex{display:flex}.dosing-flex-col{display:flex;flex-direction:column}.dosing-flex-row{display:flex;flex-direction:row}.dosing-flex-center{display:flex;align-items:center;justify-content:center;margin-top:-29px;margin-bottom:-29px}.dosing-grid{display:grid}.dosing-grid-2{display:grid;grid-template-columns:1fr;row-gap:var(--space-xl)}@media (min-width:768px){.dosing-grid-2{grid-template-columns:repeat(2,1fr);row-gap:0}}.dosing-grid-3{display:grid;grid-template-columns:1fr;gap:1.5rem;margin-top:var(--space-md)}@media (min-width:768px){.dosing-grid-3{grid-template-columns:repeat(3,1fr)}}.dosing-block{display:block}.dosing-inline{display:inline}.dosing-hidden,.dosing-hidden-mobile{display:none}@media (min-width:768px){.dosing-hidden-mobile{display:block}}.dosing-overflow-hidden{overflow:hidden}.dosing-scroll-x{overflow-x:auto}.dosing-gap-xs{gap:var(--space-xxs)}.dosing-gap-sm{gap:var(--space-sm)}.dosing-gap-sm-plus{gap:12px}.dosing-gap-md{gap:var(--space-md)}.dosing-gap-lg{gap:var(--space-lg)}.dosing-gap-xl{gap:var(--space-xl)}.dosing-gap-x-xl{column-gap:var(--space-md)}@media (min-width:768px){.dosing-gap-x-xl{column-gap:var(--space-xl)}}.dosing-space-nowrap{white-space:nowrap}.dosing-space-y-2>*+*{margin-top:8px}.dosing-button-height{height:32px}.dosing-full-width{width:100%}.dosing-w-divider{width:4px}.dosing-flex-shrink-0{flex-shrink:0}.dosing-flex-1{flex:1}.dosing-text-caption{font-size:12px;line-height:1.4}.dosing-text-body{font-size:14px;line-height:1.5}.dosing-text-base{font-size:16px;line-height:1.5}.dosing-text-xl{font-size:16px;line-height:1.3}@media (min-width:768px){.dosing-text-xl{font-size:20px}}.dosing-text-2xl{font-size:24px;line-height:1.3}.dosing-font-normal{font-weight:400}.dosing-font-medium{font-weight:500}.dosing-font-semibold{font-weight:600}.dosing-font-mono{font-family:var(--font-mono)}.dosing-leading-relaxed{line-height:1.7}.dosing-leading-snug{line-height:1.3}.dosing-tracking-wide{letter-spacing:.05em}.dosing-text-left{text-align:left}.dosing-text-center{text-align:center}.dosing-text-right{text-align:left}@media (min-width:768px){.dosing-text-right{text-align:right}}.dosing-tabular-nums{font-variant-numeric:tabular-nums}.dosing-text-primary{color:var(--color-text-primary)}.dosing-text-secondary{color:var(--color-text-body)}.dosing-text-tertiary{color:var(--color-text-label)}.dosing-text-inverse{color:var(--color-white)}.dosing-text-info{color:var(--color-info)}.dosing-text-info-strong{color:var(--color-info-strong)}.dosing-text-success{color:var(--color-success)}.dosing-text-error{color:var(--color-error)}.dosing-text-error-strong{color:var(--color-error-strong)}.dosing-text-warning{color:var(--color-warning)}.dosing-bg-card{background-color:var(--color-white)}.dosing-bg-surface{background-color:var(--color-surface)}.dosing-bg-info{background-color:var(--color-info-light)}.dosing-bg-info-strong{background-color:var(--color-info-strong)}.dosing-bg-info-light{background-color:var(--color-info-light)}.dosing-bg-success{background-color:var(--color-success)}.dosing-bg-success-light{background-color:var(--color-success-tint)}.dosing-bg-error{background-color:var(--color-error)}.dosing-bg-error-light{background-color:var(--color-error-tint)}.dosing-bg-transparent{background-color:transparent}.dosing-border-default{border-color:var(--color-border)}.dosing-border-info{border-color:var(--color-info)}.dosing-border-info-accent{border-color:var(--color-info-accent)}.dosing-border-error{border-color:var(--color-error)}.dosing-border-warning{border-color:var(--color-warning)}.dosing-border-2{border-width:4px;border-style:solid}.dosing-border-top{border-top-width:4px;border-top-style:solid}.dosing-border-bottom{border-bottom-width:4px;border-bottom-style:solid}.dosing-border-dashed{border-style:dashed}.dosing-rounded-lg{border-radius:var(--radius-md)}.dosing-rounded-xl{border-radius:var(--radius-lg)}.dosing-rounded-full{border-radius:9999px}.dosing-items-start{align-items:flex-start}.dosing-items-center{align-items:center}.dosing-justify-center{justify-content:center}.dosing-justify-between{justify-content:space-between}.dosing-focus-none:focus{outline:none;box-shadow:none}.dosing-hover-bg-surface:hover{background-color:var(--color-surface)}.dosing-hover-border-info:hover{border-color:var(--color-info)}.dosing-transition{transition-property:all;transition-timing-function:cubic-bezier(.4,0,.2,1);transition-duration:.15s}.dosing-p-6{padding:24px}.dosing-p-7{padding:var(--space-lg)}.dosing-px-0{padding-left:0;padding-right:0}.dosing-px-2{padding-left:8px;padding-right:8px}.dosing-px-3{padding-left:12px;padding-right:12px}.dosing-px-4{padding-left:16px;padding-right:16px}.dosing-py-1-5{padding-top:8px;padding-bottom:8px}.dosing-py-3{padding-top:12px;padding-bottom:12px}.dosing-py-4{padding-top:16px;padding-bottom:16px}.dosing-pt-5{padding-top:20px}.dosing-pb-2{padding-bottom:8px}.dosing-pb-4{padding-bottom:16px}.dosing-pb-5{padding-bottom:20px}.dosing-pb-10{padding-bottom:40px}.dosing-pr-8{padding-right:32px}.dosing-mt-2{margin-top:8px}.dosing-mt-4{margin-top:16px}.dosing-mt-6{margin-top:24px}.dosing-mt-8{margin-top:32px}.dosing-mb-2{margin-bottom:8px}.dosing-mb-4{margin-bottom:16px}.dosing-mb-8{margin-bottom:32px}.dosing-ml-0{margin-left:0}.dosing-ml-2{margin-left:8px}.dosing-ml-4{margin-left:16px}.dosing-ml-16{margin-left:64px}.dosing-ml-28{margin-left:var(--space-lg)}.dosing-ml-px{margin-left:4px}.dosing-mr-0{margin-right:0}.dosing-neg-mr-4{margin-right:-16px}.dosing-w-3{width:12px}.dosing-w-4{width:16px}.dosing-w-100{width:96px}.dosing-w-160{width:160px}.dosing-h-3{height:12px}.dosing-h-4{height:16px}.dosing-h-full{height:100%}.dosing-badge{display:inline-flex;align-items:center;padding:4px 12px;border-radius:var(--radius-sm);font-size:12px;font-weight:600;text-transform:uppercase;letter-spacing:.05em}.dosing-badge-borderless{border:none}.dosing-badge-info{background-color:var(--color-info-light);color:var(--color-info-strong)}.dosing-label{font-size:12px;font-weight:600;text-transform:uppercase;letter-spacing:.08em;color:var(--color-text-secondary)}.dosing-bg-warning-light{background-color:var(--color-warning-tint)}.dosing-text-info-accent{color:var(--color-info-accent)}.dosing-relative{position:relative}.dosing-grid-3-cols{display:grid;grid-template-columns:repeat(3,1fr)}.dosing-grid-gap-3{gap:12px}.dosing-grid-gap-6{gap:24px}.dosing-grid-gap-8{gap:32px}.dosing-stack-xs{gap:var(--space-xxs)}.dosing-stack-sm,.dosing-stack-xs{display:flex;flex-direction:column}.dosing-stack-sm{gap:var(--space-sm)}.dosing-stack-md{gap:var(--space-md)}.dosing-stack-lg,.dosing-stack-md{display:flex;flex-direction:column}.dosing-stack-lg{gap:var(--space-lg)}.dosing-stack-xl{display:flex;flex-direction:column;gap:var(--space-xl)}.dosing-flex-row-gap-2{display:flex;flex-direction:row;gap:8px}.dosing-border-bottom-0{border-bottom-width:0}